Selank
Selank is a synthetic heptapeptide analogue of the endogenous immunomodulatory peptide tuftsin, engineered with a Pro-Gly-Pro extension to enhance metabolic stability and CNS bioactivity. In research models it has been studied for modulation of GABAergic and monoaminergic signaling, regulation of stress-response pathways, and support of cognitive function without sedative impairment.
Batch Details: SK5-A1
Selank is a research-grade neuropeptide derived from tuftsin (a naturally occurring immunopeptide) with an added Pro-Gly-Pro tail to improve half-life and receptor engagement. It has been studied in models of stress, mood regulation, and attention, where it appears to influence anxiolytic pathways, neurotrophic signaling, and cytokine balance relevant to neuroimmune stability.
Research SignificanceInvestigation of anxiolytic-like activity without classical sedative effectsModulation of GABA-related tone and monoamine (serotonin/dopamine) signaling in CNS modelsCognitive endpoints such as attention, memory encoding, and mental clarity under stress loadImmunoregulatory effects, including regulation of inflammatory cytokine expression and neuroimmune cross-talk
Potential Research ApplicationsBehavioral neuroscience models of stress, anxiety, and resilienceStudies on cognitive performance, vigilance, and information processing under fatigueNeuroimmune interface research (peptide signaling vs. inflammatory mediators)Comparative work alongside Semax and other regulatory heptapeptides to map structure–function relationships
SpecificationsForm: Lyophilized peptide powderContent: Selank 5 mg per vialIdentity: Synthetic heptapeptide analogue of tuftsin with Pro-Gly-Pro extensionStorage: Store at −20 °C; once reconstituted, use promptly under sterile lab conditions
